Ferrari 12Cilindri 配備前六活塞、後四活塞嘅碳陶瓷煞車系統，前後輪都係通風碟。輪胎方面，配備專用嘅 Michelin Pilot Sport S5 高性能輪胎，前輪尺寸 275/35 R21，後輪 315/35 R21。呢個輪胎組合專為 12Cilindri 嘅性能特性開發，提供極佳嘅抓地力。
The Ferrari 12Cilindri features a carbon ceramic braking system with six-piston front and four-piston rear calipers, with ventilated discs all round. It rides on bespoke Michelin Pilot Sport S5 high-performance tyres – 275/35 R21 at the front and 315/35 R21 at the rear – developed specifically for the 12Cilindri's performance characteristics, offering exceptional grip.
