Mazda CX-3 配備 i-ACTIVSENSE 主動安全系統，功能包括前方碰撞預警及自動煞車、倒車時自動煞車、車道偏離警示系統（時速超過 60 公里時自動偵測行車線），以及智能照明頭燈組合。Mazda CX-3 獲得美國 IIHS「Top Safety Pick+」最高安全評級。
The Mazda CX-3 is equipped with the i-ACTIVSENSE active safety system, including forward collision warning and autonomous braking, automatic braking when reversing, lane departure warning system (activated above 60 km/h), and adaptive LED headlights. The Mazda CX-3 has achieved the IIHS "Top Safety Pick+" highest safety rating.
